How weakness in cell structure affects the host–microbiome relationship

Cells have an internal skeleton that maintains their structure and also drives their movement. Known as the cytoskeleton, ...
Medscape

Europe Moves Forward With ESR1-Driven Breast Cancer

The EMA’s recommendation follows evidence that the targeted therapy improves progression-free survival in patients whose ...

Penn and CHOP will test gene therapy for rare diseases with a new FDA trial protocol

Earlier this year, researchers at CHOP and Penn created a first-of-its-kind drug customized to a unique genetic mutation to save an infant named Baby KJ from dying of a rare liver disorder. KJ Muldoon ...

Adaptive tracking theory of molecular evolution challenges mutation neutrality

For a long time, evolutionary biologists have thought that the genetic mutations that drive the evolution of genes and ...
Daily Democrat

Plants balance adaptability in skin cells with stability in sex cells

New research led by plant biologists at UC Davis, published Nov. 10 in Proceedings of the National Academy of Sciences, reveals how plants control mutation rates in different stem cells to balance ...
JD Supra

FDA Leadership Outlines “Plausible Mechanism” Pathway for Bespoke Therapies

The US Food and Drug Administration (FDA) is proposing a new “plausible mechanism” pathway that will enable the limited ...

Aquaporin gene duplication followed by mutation in European eels restores broad solute permeability

Common ancestor eels lost the aquaporin gene encoding proteins with broad solute permeability. Researchers from the Institute ...