Adaptive tracking theory of molecular evolution challenges mutation neutrality

For a long time, evolutionary biologists have thought that the genetic mutations that drive the evolution of genes and ...

How cells preserve mitochondrial DNA quality across generations

Researchers from Karolinska Institutet have discovered how mammalian cells prevent the gradual buildup of harmful mutations ...
CURE

FDA Fast Tracks FOG-001 After Early Tumor Shrinkage in Desmoid Tumors

FOG-001 received fast track designation after early study results showed tumor shrinkage in all evaluable patients with ...

Aptose Biosciences, Inc.: Aptose Reports Third Quarter 2025 Results

Tuspetinib Continues to Demonstrate Excellent Safety and Complete Responses in the TUSCANY Clinical Trial of Tuspetinib in AML Triple Drug Frontline Therapy at Increased Dose LevelsPatients are Now Be ...

Mosquito reproduction may hinge on E93 gene that links blood meals to energy use

Mosquito-borne diseases, including dengue, Zika, and yellow fever, continue to pose a significant global health threat, ...

Overlooked layer of DNA may explain disease risk, severity

Scientists at The Hospital for Sick Children (SickKids) have revealed a previously overlooked layer of genetic variation that ...
eLife

Nanoscopy Reveals Heparan Sulfate Clusters as Docking Sites for SARS-CoV-2 Attachment and Entry

Virus entry is thought to involve binding a unique receptor for cell attachment and cytosolic entry. For SARS-CoV-2 underlying the COVID-19 pandemic, angiotensin- converting enzyme 2 (ACE2) is widely ...
University of California, San Francisco

How to Thwart Cancer: Drug the Cells It Uses to Grow and Shapeshift

Senescent fibroblasts are aging cells in connective tissue that no longer divide and protect against tumor development. Yet, these same cells can promote cancer growth in a laboratory setting.Until ...