The coronavirus disease 2019 (COVID-19) pandemic underscored the need for the development of tools that can visualize immune system activity in the context of viral inflammation. Although [18F]FDG PET ...

Leucine-rich repeat–containing protein 15 (LRRC15) is a cell surface protein that has emerged as a significant biomarker in cancer biology. This protein is minimally expressed in normal healthy tissue ...

Dr. Bernd Pichler is a distinguished pioneer in preclinical and translational imaging, renowned for his groundbreaking work ...

RECIST was developed in 2000 by the National Cancer Institute, European Organization for Research and Treatment of Cancer, and National Cancer Institute of Canada, with revision to RECIST 1.1 in 2009 ...

We present an overview of our prospective fibroblast-activation protein inhibitor (FAPI) registry study across a 3-y period, with head-to-head comparison of tumor uptake in 68Ga-FAPI and 18F-FDG PET, ...

The immune-fibrosis axis plays a critical role in cardiac remodeling after acute myocardial infarction. Imaging approaches to monitor temporal inflammation and fibroblast activation in mice have seen ...

5B1 is a fully human, monoclonal antibody that has shown promise for the PET imaging of cancers expressing carbohydrate antigen 19.9 (CA19.9)—a carbohydrate prevalent in cells with aberrant ...

Recently introduced PET systems using silicon photomultipliers with digital readout (dPET) have an improved timing and spatial resolution, aiming at a better image quality than conventional PET (cPET) ...

The 18F-labeled fibroblast activation protein inhibitor (FAPI) [18F]FAPI-74 has the benefit of a higher synthetic yield and better image resolution than 68Ga-labeled FAPI. We preliminarily evaluated ...

High expression of prostate-specific membrane antigen (PSMA) is not limited to prostate cancer but can be found in other tumor entities, such as hepatocellular carcinoma (HCC), and could possibly be ...

PET is a powerful molecular imaging technique that can provide functional information on living objects. However, the spatial resolution of PET imaging has been limited to around 1 mm, which makes it ...

SPECT imaging using isotopes emitting high-energy gamma or bremsstrahlung photons has important applications in oncology and is used for both diagnosis and therapy monitoring. Examples of applications ...