For the first time ever, a research team has peered inside a human cell to view Mediator-bound pre-initiation complex, a multi-subunit machine responsible for regulating gene expression. For the first ...
Global transcriptional analyses have revealed that the vast majority of the human genome is dynamically and differentially transcribed to produce a range and complexity of lncRNAs 1. These ...
As a member of the Phylum, Cnidaria, hydra arose early during metazoan evolution before divergence of the protosome and deuterostome branches. Its body plan is organized as a gastric tube with a mouth ...
Our results reveal that RNA structure governs a complex posttranscriptional regulatory program of α-1-antitrypsin expression. Crucially, these findings describe a mechanism by which genetic ...
The profusion of genome-wide association studies (GWAS) in recent years have uncovered hundreds of genetic variants linked to neurodegenerative diseases. Yet the wealth of sequences hasn’t yielded an ...
Scientists at St. Jude Children's Research Hospital and Northwestern University identified a previously unknown treatment ...
Researchers from Northwestern University during a recent study, for the first time peered inside a human cell in order to have a look at a multi-subunit machine that is responsible for regulating gene ...
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